The journal of extra-corporeal technology · 2026
Extracorporeal carbon dioxide removal (ECCO2R) in post lung transplant patients.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Zavala Gómez Mariana N, Chinchilla Lopez Elisa, Garza Trevino Ricardo, Borbolla Paola, Bernal Heinzel Sebastian, Lozano Miranda Gilberto, Méndez Allan, Chavarria Martinez Uriel, Wong Manuel, Camacho Ortiz Adrián, Rizo Topete Lilia M, Sánchez Salazar Sergio
Аннотация
Extracorporeal carbon dioxide removal (ECCO2R) has emerged as a promising adjunctive therapy to mitigate hypercapnia and reduce invasive mechanical ventilation (IMV) settings. We present the cases of two post-lung transplant patients with severe hypercapnia and respiratory failure who were successfully treated with the ECCO2R. In both cases, we used a venovenous ECCO2R (V-ECCO2R) system, employing the Prismalung™ oxygenator integrated into a Prismaflex™ continuous renal replacement therapy (CRRT) platform. This technique proved efficacy in correcting hypercapnia, improving ventilatory parameters, and facilitating lung-protective strategies in post-lung transplant patients with respiratory failure. This technique represents a valuable adjunct to conventional mechanical ventilation, particularly in cases where hypercapnia poses a risk to graft function and patient stability. Further studies are warranted to establish optimal patient selection and refine treatment protocols for ECCO2R implementation in critical care settings.