Annals of clinical and translational neurology · 2023
No pain, no strain: Targin® mitigates pain and constipation following spinal cord injury.
Клинический случайПоддержка исследования: вне правительства СШАСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
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Sachdeva Rahul, Hosseinzadeh Ali, Rizzardo Aaron, Maharaj Andrea, Berger Michael, Krassioukov Andrei
Аннотация
BACKGROUND: Opioids effectively reduce chronic pain, but present significant side effects including opioid-induced constipation. Oxycodone/naloxone decreases pain and constipation in cancer patients, however its effect on spinal cord injury population remains understudied.
METHODS: We assessed whether oxycodone/naloxone reduces pain, constipation, and severity of autonomic dysreflexia in an individual with spinal cord injury. A 55-year-old male with C5 lesion presented with chief complaint of chronic pain received 5/2.5 mg and 20/10 mg oxycodone/naloxone for 6 and 2 weeks, respectively.
RESULTS: Oxycodone/naloxone improved pain, bowel function, and autonomic dysreflexia severity.
INTERPRETATION: Oxycodone/naloxone was effective in managing chronic pain and constipation in the studied case.
METHODS: We assessed whether oxycodone/naloxone reduces pain, constipation, and severity of autonomic dysreflexia in an individual with spinal cord injury. A 55-year-old male with C5 lesion presented with chief complaint of chronic pain received 5/2.5 mg and 20/10 mg oxycodone/naloxone for 6 and 2 weeks, respectively.
RESULTS: Oxycodone/naloxone improved pain, bowel function, and autonomic dysreflexia severity.
INTERPRETATION: Oxycodone/naloxone was effective in managing chronic pain and constipation in the studied case.