Techniques in coloproctology · 2025
Bilateral posterior tibial nerve stimulation as a neuromodulation strategy for obstructed defecation: a randomized controlled trial.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Abouelnasr Anwar Ashraf, Hany Mohamed
Аннотация
BACKGROUND: Obstructed defecation syndrome (ODS) is a prevalent pelvic floor disorder, often impairing patients' quality of life. Noninvasive therapies, including posterior tibial nerve stimulation (PTNS), have been explored as alternative treatments. This study evaluates the efficacy of bilateral transcutaneous posterior tibial nerve stimulation (BT-PTNS) compared to medical treatment alone in patients with ODS without anatomical abnormalities.
METHODS: A prospective randomized controlled study was conducted on 50 patients diagnosed with ODS. Patients were randomly assigned into two groups: group A received BT-PTNS sessions three times weekly for 6-12 weeks alongside medical treatment, while group B received medical treatment only. Outcomes were assessed using the Modified Obstructed Defecation Syndrome (MODS) score, Patient Assessment of Constipation Quality of Life (PAC-QOL) questionnaire, and quantitative electromyography of pelvic floor muscles. Statistical analysis was performed using SPSS software.
RESULTS: Group A exhibited a significant reduction in MODS scores (mean decrease = 10 points) compared to group B (mean decrease = 4 points) after 6 weeks (p < 0.001). PAC-QOL scores improved significantly in group A (65% reduction) compared to group B (37% reduction). Electromyographic analysis in group A showed significant improvement in amplitude, number of motor unit turns, and duration (p < 0.001). No adverse events were reported in either group.
CONCLUSION: BT-PTNS is a safe and effective noninvasive treatment for ODS without anatomical abnormalities, significantly improving symptom severity and quality of life. Further multicentric trials are warranted to standardize treatment protocols and assess long-term outcomes.
TRIAL REGISTRATION: Clinical Trial Number IORG0008812; E/C.S/N.R2/2017.
METHODS: A prospective randomized controlled study was conducted on 50 patients diagnosed with ODS. Patients were randomly assigned into two groups: group A received BT-PTNS sessions three times weekly for 6-12 weeks alongside medical treatment, while group B received medical treatment only. Outcomes were assessed using the Modified Obstructed Defecation Syndrome (MODS) score, Patient Assessment of Constipation Quality of Life (PAC-QOL) questionnaire, and quantitative electromyography of pelvic floor muscles. Statistical analysis was performed using SPSS software.
RESULTS: Group A exhibited a significant reduction in MODS scores (mean decrease = 10 points) compared to group B (mean decrease = 4 points) after 6 weeks (p < 0.001). PAC-QOL scores improved significantly in group A (65% reduction) compared to group B (37% reduction). Electromyographic analysis in group A showed significant improvement in amplitude, number of motor unit turns, and duration (p < 0.001). No adverse events were reported in either group.
CONCLUSION: BT-PTNS is a safe and effective noninvasive treatment for ODS without anatomical abnormalities, significantly improving symptom severity and quality of life. Further multicentric trials are warranted to standardize treatment protocols and assess long-term outcomes.
TRIAL REGISTRATION: Clinical Trial Number IORG0008812; E/C.S/N.R2/2017.