The simplex (differentiated) variant of vulvar intraepithelial neoplasia.

BACKGROUND

The simplex (differentiated) variant of vulvar intraepithelial neoplasia is rarely reported. It is regarded as more likely than "classic" carcinoma in situ to be associated with invasion and can be easily mistaken for benign lesions.

OBJECTIVE

The objective was to present a case of simplex variant of vulvar intraepithelial neoplasia in a 67-year-old woman that was initially misdiagnosed as lichen simplex chronicus.

METHODS

A case report is reported and the literature is reviewed.

RESULTS

Surgical excision with a free margin of 5 mm was performed and no evidence of recurrence was noted during the follow-up period of 6 months.

CONCLUSION

The simplex vulvar intraepithelial neoplasia is an easily overlooked premalignant disease, and it can be cured with surgical treatment if diagnosed correctly and early.