Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2013
Genetic similarity between Taenia solium cysticerci collected from the two distant endemic areas in North and North East India.
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Sharma Monika, Devi Kangjam Rekha, Sehgal Rakesh, Narain Kanwar, Mahanta Jagadish, Malla Nancy
Аннотация
Taenia solium taeniasis/cysticercosis is a major public health problem in developing countries. This study reports genotypic analysis of T. solium cysticerci collected from two different endemic areas of North (Chandigarh) and North East India (Dibrugarh) by the sequencing of mitochondrial cytochrome c oxidase subunit 1 (cox1) gene. The variation in cox1 sequences of samples collected from these two different geographical regions located at a distance of 2585 km was minimal. Alignment of the nucleotide sequences with different species of Taenia showed the similarity with Asian genotype of T. solium. Among 50 isolates, 6 variant nucleotide positions (0.37% of total length) were detected. These results suggest that population in these geographical areas are homogenous.