International dental journal · 2026
Effect of Acmella Oleracea (Jambu) Bioadhesive Film on Post-Bleaching Dental Sensitivity: A Randomised Clinical Trial.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Silva Allícia Drielly Abreu, Wanderley Marina Lima, Leite Diana Ferreira, de Oliveira Beatriz Lopes, Fernandes Brian Willian de Souza, Dias Dayane Dos Reis Costa, Silva Cecy Martins, Xavier Gabriela Monteiro Barbosa, Araújo Jesuina Lamartine Nogueira
Аннотация
OBJECTIVE: To evaluate an experimental bioadhesive film containing Acmella oleracea (jambu) extract in reducing post-bleaching dental sensitivity associated with 35% hydrogen peroxide (HP), as well as its influence on colour change and oral health-related quality of life (OHRQoL).
MATERIALS AND METHODS: 72 volunteers were randomised into 3 groups: GCP (placebo control), GKF (5% potassium nitrate + 2% sodium fluoride), and GAO (bioadhesive film of Acmella oleracea). Before bleaching, the corresponding desensitising product was applied to each group for 10 minutes. Bleaching was performed using 35% HP in 3 sessions, with a 7-day interval between them. Post-bleaching dental sensitivity was assessed using a visual analogue scale (VAS) over a 21-day follow-up period. Colour (ΔE00) and lightness (L) were measured at baseline (T0) and 7 days after the third session (Tf). The impact on OHRQoL was evaluated using the DHEQ-15 questionnaire. Non-parametric tests (Friedman, Wilcoxon, Kruskal-Wallis with post hoc) and ANOVA were applied (α = 5%), with effect sizes calculated.
RESULTS: Significant intergroup differences in post-bleaching dental sensitivity were observed (P < .001), with a very large effect size (ε² = 0.85). The GAO group showed the lowest sensitivity levels, while the GCP group presented the highest. Intragroup analysis demonstrated a significant reduction in sensitivity over time (P < .001; Kendall's W = 0.95). All groups showed effective bleaching, with no significant differences in ΔE₀₀ (P = .508) or L values (T0: P = .655; Tf: P = .421). Significant improvements in OHRQoL were observed in the GKF and GAO groups (P < .0001), with intergroup differences at the final time point favouring these treatments.
CONCLUSIONS: The bioadhesive film containing Acmella oleracea extract reduced post-bleaching dental sensitivity without compromising the esthetic outcome. Improvements in oral health-related quality of life were observed following treatment.
CLINICAL RELEVANCE: A bioadhesive film with Acmella oleracea (jambu) extract effectively reduced post-bleaching dental sensitivity after 35% hydrogen peroxide application.
MATERIALS AND METHODS: 72 volunteers were randomised into 3 groups: GCP (placebo control), GKF (5% potassium nitrate + 2% sodium fluoride), and GAO (bioadhesive film of Acmella oleracea). Before bleaching, the corresponding desensitising product was applied to each group for 10 minutes. Bleaching was performed using 35% HP in 3 sessions, with a 7-day interval between them. Post-bleaching dental sensitivity was assessed using a visual analogue scale (VAS) over a 21-day follow-up period. Colour (ΔE00) and lightness (L) were measured at baseline (T0) and 7 days after the third session (Tf). The impact on OHRQoL was evaluated using the DHEQ-15 questionnaire. Non-parametric tests (Friedman, Wilcoxon, Kruskal-Wallis with post hoc) and ANOVA were applied (α = 5%), with effect sizes calculated.
RESULTS: Significant intergroup differences in post-bleaching dental sensitivity were observed (P < .001), with a very large effect size (ε² = 0.85). The GAO group showed the lowest sensitivity levels, while the GCP group presented the highest. Intragroup analysis demonstrated a significant reduction in sensitivity over time (P < .001; Kendall's W = 0.95). All groups showed effective bleaching, with no significant differences in ΔE₀₀ (P = .508) or L values (T0: P = .655; Tf: P = .421). Significant improvements in OHRQoL were observed in the GKF and GAO groups (P < .0001), with intergroup differences at the final time point favouring these treatments.
CONCLUSIONS: The bioadhesive film containing Acmella oleracea extract reduced post-bleaching dental sensitivity without compromising the esthetic outcome. Improvements in oral health-related quality of life were observed following treatment.
CLINICAL RELEVANCE: A bioadhesive film with Acmella oleracea (jambu) extract effectively reduced post-bleaching dental sensitivity after 35% hydrogen peroxide application.