Lower urinary tract symptoms · 2026
Early Physiologic Deobstruction After 980-nm Diode-Laser Contact Prostate Vaporization: Analysis of Evaluable Paired Pressure-Flow Studies From a Consecutive Cohort.
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Kurano Yoshitaka, Shimizu Nobutaka, Ide Yukimasa, Togo Mio, Yoshimura Rie, Shigehisa Ryu, Yamamoto Shinkuro, Fukuhara Hideo, Fukata Satoshi, Saito Motoaki, Inoue Keiji
Аннотация
OBJECTIVES: To describe early physiologic deobstruction after contemporary 980-nm diode-laser contact vaporization of the prostate (CVP) in patients with evaluable paired preoperative and 3-month postoperative pressure-flow studies (PFS).
METHODS: This single-center retrospective cohort included 94 consecutive men who underwent CVP between March 2023 and August 2025. Paired full PFS was evaluable in 48 patients. Baseline characteristics were compared between patients with and without evaluable paired PFS. Perioperative outcomes, symptom scores, and complications were summarized in the full cohort, whereas paired PFS parameters were analyzed in the paired PFS cohort.
RESULTS: In the full cohort, IPSS total and voiding scores and QOL improved from 1 month postoperatively, whereas storage symptom improvement was more gradual. OABSS showed transient mild worsening at 1 month, followed by improvement. In the paired PFS cohort, voiding parameters improved markedly, with significant reductions in BOOI, PdetQmax, and PVR and increases in Qmax and voided volume. In contrast, filling-phase parameters, including first desire to void, normal desire to void, maximum cystometric capacity, and bladder compliance, showed limited short-term changes. Postoperative complications occurred in 31/94 patients (33.0%), accounting for 37 events. The most common complications were transient urinary retention and urinary tract infection, each occurring in 12/94 patients (12.8%).
CONCLUSIONS: CVP was associated with substantial early outlet relief on paired PFS, accompanied by improvements in patient-reported symptoms. Early filling-phase changes were limited, suggesting that bladder storage recovery may lag behind outlet relief. Prospective comparative studies with longer follow-up are needed.
METHODS: This single-center retrospective cohort included 94 consecutive men who underwent CVP between March 2023 and August 2025. Paired full PFS was evaluable in 48 patients. Baseline characteristics were compared between patients with and without evaluable paired PFS. Perioperative outcomes, symptom scores, and complications were summarized in the full cohort, whereas paired PFS parameters were analyzed in the paired PFS cohort.
RESULTS: In the full cohort, IPSS total and voiding scores and QOL improved from 1 month postoperatively, whereas storage symptom improvement was more gradual. OABSS showed transient mild worsening at 1 month, followed by improvement. In the paired PFS cohort, voiding parameters improved markedly, with significant reductions in BOOI, PdetQmax, and PVR and increases in Qmax and voided volume. In contrast, filling-phase parameters, including first desire to void, normal desire to void, maximum cystometric capacity, and bladder compliance, showed limited short-term changes. Postoperative complications occurred in 31/94 patients (33.0%), accounting for 37 events. The most common complications were transient urinary retention and urinary tract infection, each occurring in 12/94 patients (12.8%).
CONCLUSIONS: CVP was associated with substantial early outlet relief on paired PFS, accompanied by improvements in patient-reported symptoms. Early filling-phase changes were limited, suggesting that bladder storage recovery may lag behind outlet relief. Prospective comparative studies with longer follow-up are needed.