F&S science · 2026
Comparison of hysterosalpingo-foam sonography vs. hysterosalpingography: a prospective observational study.
СтатьяНаблюдательное исследованиеСравнительное исследованиеНазвание и аннотация: Перевод в очереди
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Luque González Pablo, Morales Bueno Ángela, Del Río Romero Inmaculada, Dueñas Díez José Luis, Guadix Martín María Del Pilar
Аннотация
OBJECTIVE: To study the diagnostic concordance and tolerability of hysterosalpingo-foam sonography (HyFoSy) compared with hysterosalpingography (HSG) in the evaluation of tubal patency.
DESIGN: Prospective observational study conducted between 2023 and 2024 in a Spanish hospital, using a within-subject comparative design.
SUBJECTS: A total of 117 women undergoing fertility evaluation.
EXPOSURE: All participants underwent both HyFoSy and HSG for assessment of tubal patency.
MAIN OUTCOME MEASURES: Diagnostic concordance between HyFoSy and HSG (Cohen's kappa coefficient), pain assessment using the visual analogue scale (VAS), and procedure-related complications.
RESULTS: Complete concordance between HyFoSy and hysterosalpingography was obtained in 100 patients (85.4%), of whom 85 had normal patency, and 15 had some patency defect (moderate agreement with a kappa coefficient of 0.575). In 12 patients (10.2%), there were discordant diagnoses, and in five patients (4.3%), concordance could not be assessed. Hysterosalpingo-foam sonography was better tolerated in terms of reported pain, while HSG had a significantly higher median pain score. Only minor complications were recorded during the performance of both techniques, mainly slight vaginal bleeding and vasovagal discomfort.
CONCLUSIONS: Our study shows HyFoSy is an effective, safe and better-tolerated technique than HSG, with a similar diagnostic rate for the study of tubal patency defects.
DESIGN: Prospective observational study conducted between 2023 and 2024 in a Spanish hospital, using a within-subject comparative design.
SUBJECTS: A total of 117 women undergoing fertility evaluation.
EXPOSURE: All participants underwent both HyFoSy and HSG for assessment of tubal patency.
MAIN OUTCOME MEASURES: Diagnostic concordance between HyFoSy and HSG (Cohen's kappa coefficient), pain assessment using the visual analogue scale (VAS), and procedure-related complications.
RESULTS: Complete concordance between HyFoSy and hysterosalpingography was obtained in 100 patients (85.4%), of whom 85 had normal patency, and 15 had some patency defect (moderate agreement with a kappa coefficient of 0.575). In 12 patients (10.2%), there were discordant diagnoses, and in five patients (4.3%), concordance could not be assessed. Hysterosalpingo-foam sonography was better tolerated in terms of reported pain, while HSG had a significantly higher median pain score. Only minor complications were recorded during the performance of both techniques, mainly slight vaginal bleeding and vasovagal discomfort.
CONCLUSIONS: Our study shows HyFoSy is an effective, safe and better-tolerated technique than HSG, with a similar diagnostic rate for the study of tubal patency defects.