Fertility and sterility · 1993
Sex preselection through albumin separation of sperm.
СтатьяНазвание и аннотация: Перевод в очереди
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Beernink F J, Dmowski W P, Ericsson R J
Аннотация
OBJECTIVE: To determine if passage of sperm through columns of liquid albumin before their use in artificial insemination could affect the sex ratio at birth.
DESIGN: Sperm were isolated by layering over columns of liquid albumin. The isolated fractions were inseminated into the uterus on the presumptive day of ovulation.
SETTING: Patients were treated in 65 clinical practices (Sperm Centers) located both in this country (57) and abroad (8).
PATIENTS: Individuals were self-selected by their desire to have a child of a specified sex.
MAIN OUTCOME MEASURE: The sex of offspring resulting from the insemination of isolated sperm.
RESULTS: Insemination with sperm isolated to enhance male sex preselection produced 71% and 76% males depending on the technique. Use of isolated sperm in women who were taking clomiphene citrate was associated with a 69% birth of females.
CONCLUSIONS: Separation of sperm on columns of liquid albumin can affect the sex ratio at birth.
DESIGN: Sperm were isolated by layering over columns of liquid albumin. The isolated fractions were inseminated into the uterus on the presumptive day of ovulation.
SETTING: Patients were treated in 65 clinical practices (Sperm Centers) located both in this country (57) and abroad (8).
PATIENTS: Individuals were self-selected by their desire to have a child of a specified sex.
MAIN OUTCOME MEASURE: The sex of offspring resulting from the insemination of isolated sperm.
RESULTS: Insemination with sperm isolated to enhance male sex preselection produced 71% and 76% males depending on the technique. Use of isolated sperm in women who were taking clomiphene citrate was associated with a 69% birth of females.
CONCLUSIONS: Separation of sperm on columns of liquid albumin can affect the sex ratio at birth.