Meta-analysis of perioperative and renal functional outcomes of Robot-Assisted Partial Ureterectomy (RASU) versus complete Nephroureterectomy (RARNU) for upper tract urothelial tumors.

This meta-analysis investigated the comparative effectiveness of two robotic surgical interventions—the kidney-sparing approach (segmental ureterectomy) was compared against the traditional radical procedure—in treating Tumor of the Ureter, with a focus on perioperative results and renal function preservation. Following the PRISMA guidelines, a systematic literature search was performed across multiple electronic databases was conducted in databases. A meta-analysis was performed on the extracted data, evaluating outcomes such as surgical time, volume of intraoperative bleeding, postoperative complications, duration of hospitalization, glomerular filtration rate within 3 months, incidence of positive margins, cases of recurrence, postoperative tumor grade, number of lymph node dissections, proportion of ≥ pT2 stage, and Lymph node tumor burden. Operative duration, volume of intraoperative bleeding, incidence of postoperative morbidity, and the 3-month glomerular filtration rate were designated as the primary outcome measures. Four studies involving 683 patients were included. We identified a total of 1045 records through our literature search. After eliminating overlapping publications and screening, 4 studies (3 retrospective and 1 prospective) involving 683 patients (the study population comprised 683 patients, with 108 allocated to the RASU cohort and 575 to the RARNU cohort.) were finally included. Analysis of demographic and clinical features, such as age, sex, BMI, and renal function prior to surgery, showed no highly significant disparities between the cohorts. except for with 3 months eGFR (P = 0.02), Post operative complications (P = 0.03).