Head & neck · 2025
Health-Related Quality of Life in Patients Undergoing Surgery for Primary Hyperparathyroidism: Patient Reported Outcome Measures.
СтатьяПоддержка NIH: внешняя программаНазвание и аннотация: Перевод в очереди
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Trinh Lily N, Okose Okenwa C, Abdelhamid-Ahmed Amr H, Saito Yoshiyuki, Russell Marika D, Athni Tejas S, Karcioglu Amanda Silver, Cheung Anthony Y, Srikanthan Adithya, Alcaro Christina, Sistovaris Anthea, Behr Ian J, Soffer Justin M, Wang Bo, Wong Sam, Altan Defne, Salem Farhad, Zavaro Elias, Maneeprasopchoke Prachya, Larrabee Katherine, Kamani Dipti, Almquist Martin, Triponez Frédéric, Shin Jennifer J, Randolph Gregory W
Аннотация
BACKGROUND: Parathyroidectomy is typically curative for primary hyperparathyroidism (PHPT) and may lead to health-related quality of life (HRQL) improvements. We aim to evaluate general and disease-specific HRQL changes in patients undergoing surgery for PHPT from their perspective.
METHODS: Patients completed three patient-reported outcome measure (PROM) surveys before and after surgery: (1) Worry survey; (2) Voice Handicap Index-10 (VHI-10); and (3) Patient-Reported Outcome Measurement Information System Global-10 (PROMIS).
RESULTS: Forty-four patients were included with a median age of 65 years, with 39 females (89%) included. Thirty-two patients (73%) had a single adenoma, and 12 (27%) had multigland disease (parathyroid hyperplasia). Worry scores related to parathyroid cancer, parathyroid surgery, and parathyroid-related problems significantly improved post-operatively (p < 0.05). On PROMIS assessment, there were improved scores in the physical health domain, mental health domain, and general health following parathyroid surgery for PHPT (p < 0.05).
CONCLUSION: Patients with PHPT demonstrated significant improvements in HRQL following surgery.
METHODS: Patients completed three patient-reported outcome measure (PROM) surveys before and after surgery: (1) Worry survey; (2) Voice Handicap Index-10 (VHI-10); and (3) Patient-Reported Outcome Measurement Information System Global-10 (PROMIS).
RESULTS: Forty-four patients were included with a median age of 65 years, with 39 females (89%) included. Thirty-two patients (73%) had a single adenoma, and 12 (27%) had multigland disease (parathyroid hyperplasia). Worry scores related to parathyroid cancer, parathyroid surgery, and parathyroid-related problems significantly improved post-operatively (p < 0.05). On PROMIS assessment, there were improved scores in the physical health domain, mental health domain, and general health following parathyroid surgery for PHPT (p < 0.05).
CONCLUSION: Patients with PHPT demonstrated significant improvements in HRQL following surgery.