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DOI 10.1007/s00392-003-0998-0

Медицинская библиотека · Zeitschrift fur Kardiologie · 2003

[Intraoperative cooled-tip radiofrequency ablation in patients with atrial fibrillation undergoing open heart surgery].

Lemke B, Khargi K, Grewe P H, Kuschkowitz F, Lawo T, Calcum B, Mügge A, Laczkovics A, Müller K-M, Deneke T

Клиническое исследованиеСравнительное исследованиеАннотация на английскомСтатьяРандомизированное исследованиеПеревод в очереди

Аннотация

METHODS

A total of 113 patients with chronic permanent (104) or paroxysmal (9) atrial fibrillation underwent open heart surgery plus an additional antiarrhythmic procedure using saline-irrigated cooled-tip radiofrequency ablation (SICTRA) for biatrial or left atrial linear lesions. Ablation was performed with steps of short (5 seconds) ablation around the pulmonary vein ostia and interconnecting lines. Postoperative complications and conversions to sinus rhythm were followed up (mean follow-up duration 17+/-14 months).

RESULTS

Of the 113 patients, 16 died during follow-up (day 3 up to 33 months) resulting in a cumulative survival of 79% (2 sudden cardiac deaths, 2 gastrointestinal bleedings, 1 renal bleeding, 2 mediastinitis, 1 endocarditis, 1 hemorrhagic insult, 2 respiratory insufficiencies and 2 unknown). Three patients died between day 3 and 6 (30-day mortality 3%) due to low cardiac output. Complications occurred in 19% of the patients including 4% bleeding, 1% pneumothorax, 3% sternal dehiscence, 3% reversible low cardiac output, 6% reversible respiratory insufficiency, 2% TIAs and 1% intra aortal balloon pump implantation. Conversion to sinus rhythm usually occurred spontaneously within 6 months resulting in a cumulative percentage of 80% in sinus rhythm. In these patients, 85% showed biatrial contraction.

CONCLUSIONS

SICTRA to treat atrial fibrillation can safely and effectively be combined with different surgical procedures. Mortality and complication rates are comparable to cardiac surgery without antiarrhythmic procedures. No severe procedure-related complications were noted when a stepwise ablation approach during open heart surgery was used. Antiarrhythmic surgical procedures are highly effective in restoring sinus rhythm in patients with atrial fibrillation. Is a modified approach using intraoperatively cooled-tip radiofrequency ablation to induce linear lesions safe and effective in the treatment of atrial fibrillation in cardiosurgical patients?

Для цитирования: Lemke B, Khargi K, Grewe P H, Kuschkowitz F, Lawo T, Calcum B, Mügge A, Laczkovics A, Müller K-M, Deneke T. [Intraoperative cooled-tip radiofrequency ablation in patients with atrial fibrillation undergoing open heart surgery].. Zeitschrift fur Kardiologie. 2003. DOI: 10.1007/s00392-003-0998-0.

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