Endocrine connections · 2026
Depression and Distress in Pediatric Type 1 Diabetes: A Latin American Multicenter Study.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Hirschler Valeria, Gonzalez Claudio D, Benitez Amanda, Marassi Andrea Escalante, Sobrero Angela Figueroa, Bogado Ernesto, Roussos Adriana, Gaete Laura, Arrigo Angeles, Florencia Grabois, Andres Eugenia, Arzamendia Maria Laura, Rojas Godoy Juan Pablo, Codner Etel, Araujo Luciana, Palacios Porta Luis F, Molinari Claudia, Witte Daniel R
Аннотация
OBJECTIVE: To determine (1) the prevalence of depressive symptoms and diabetes-related distress and (2) the association between their combined presence and metabolic outcomes in Latin American children with type 1 diabetes mellitus (T1DM).
METHODS: This cross-sectional study included children with T1DM of> 1 year's duration from 10 diabetes centers in Argentina and Chile. Age, sex, socioeconomic status (SES), and HbA1c were evaluated. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D; range 0-60; depression ≥16) and diabetes distress using the Problem Areas in Diabetes (PAID; range 0-80; distress ≥40). Spearman correlation, Phi coefficient, and multivariable logistic regression were used for statistical analysis.
RESULTS: Among 244 children (50% female), median age was 13.4 years (IQR 11.3-15.0), and median HbA1c was 8.3% (IQR 7.2-9.5). Depressive symptoms were present in 52% of participants and diabetes-distress in 26.6%. The agreement between CES-D and PAID categorical thresholds was fair (Phi = 0.39). The Both-1 group (n = 55; 22.5%) (high CES-D and PAID ) showed an inverse Spearman correlation with SES (r = -0.32, p < 0.01) and a positive correlation with HbA1c (r = 0.30, p < 0.01). In multivariable logistic regression, higher HbA1c (OR 1.34; 95% CI 1.1-1.6) and lower SES (OR 0.36; 95% CI 0.2-0.6) were independently associated with the Both-1 group (high CES-D and PAID), adjusted for age, sex, and BMI.
CONCLUSION: In Latin American children with T1DM, the combined presence of depressive symptoms and diabetes-related distress was associated with poorer metabolic control and lower SES.
METHODS: This cross-sectional study included children with T1DM of> 1 year's duration from 10 diabetes centers in Argentina and Chile. Age, sex, socioeconomic status (SES), and HbA1c were evaluated. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D; range 0-60; depression ≥16) and diabetes distress using the Problem Areas in Diabetes (PAID; range 0-80; distress ≥40). Spearman correlation, Phi coefficient, and multivariable logistic regression were used for statistical analysis.
RESULTS: Among 244 children (50% female), median age was 13.4 years (IQR 11.3-15.0), and median HbA1c was 8.3% (IQR 7.2-9.5). Depressive symptoms were present in 52% of participants and diabetes-distress in 26.6%. The agreement between CES-D and PAID categorical thresholds was fair (Phi = 0.39). The Both-1 group (n = 55; 22.5%) (high CES-D and PAID ) showed an inverse Spearman correlation with SES (r = -0.32, p < 0.01) and a positive correlation with HbA1c (r = 0.30, p < 0.01). In multivariable logistic regression, higher HbA1c (OR 1.34; 95% CI 1.1-1.6) and lower SES (OR 0.36; 95% CI 0.2-0.6) were independently associated with the Both-1 group (high CES-D and PAID), adjusted for age, sex, and BMI.
CONCLUSION: In Latin American children with T1DM, the combined presence of depressive symptoms and diabetes-related distress was associated with poorer metabolic control and lower SES.