Bilateral episcleritis as a manifestation of cutaneous leukocytoclastic vasculitis.

PURPOSE: The authors describe how bilateral episcleritis can be a sign of active systemic disease and can respond to treatment in a patient with cutaneous leukocytoclastic vasculitis.

DESIGN

Case report.

METHODS

Comprehensive ophthalmic and physical examination and color photography were used to monitor inflammation and its response to systemic immunosuppression.

RESULTS

Systemic cyclophosphamide caused regression of systemic symptoms, cutaneous lesions, and episcleritis. After an 8-month follow-up, the patient has not had a systemic or ocular recurrence.

CONCLUSION

Episcleritis may be a manifestation of cutaneous leukocytoclastic vasculitis. Careful examination of ocular inflammation is important in monitoring systemic disease and treatment.