International journal of surgery case reports · 2026
Spontaneous Achilles tendon rupture as the initial presentation of ochronosis: a case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
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Al-Zagebah Ahmad, Elazab Mohamed, Muhtaseb Rahaf, Tamimi Shaymaa N S, Makhlouf Taha Z
Аннотация
INTRODUCTION: Alkaptonuria (AKU) is a rare autosomal recessive metabolic disorder characterized by homogentisic acid accumulation leading to ochronosis, which weakens connective tissues and may rarely affect tendons.
PRESENTATION OF CASE: A 43-year-old man presented with sudden right ankle pain and functional loss without preceding trauma. Examination revealed a palpable gap and pigmentation of the sclera and ear. Intraoperatively, the Achilles tendon was friable and black. Histopathology confirmed ochronotic degeneration. Surgical repair using a modified Krackow suture with intraosseous anchoring achieved stable fixation and uneventful recovery.
DISCUSSION: This case illustrates spontaneous Achilles tendon rupture as an initial manifestation of AKU. Oxidative stress-induced collagen degeneration leads to tendon fragility. Recognition of characteristic pigmentation and histological features is essential for diagnosis.
CONCLUSION: Ochronosis should be considered in unexplained tendon ruptures. Surgical repair and metabolic management, including nitisinone, can optimize outcomes.
PRESENTATION OF CASE: A 43-year-old man presented with sudden right ankle pain and functional loss without preceding trauma. Examination revealed a palpable gap and pigmentation of the sclera and ear. Intraoperatively, the Achilles tendon was friable and black. Histopathology confirmed ochronotic degeneration. Surgical repair using a modified Krackow suture with intraosseous anchoring achieved stable fixation and uneventful recovery.
DISCUSSION: This case illustrates spontaneous Achilles tendon rupture as an initial manifestation of AKU. Oxidative stress-induced collagen degeneration leads to tendon fragility. Recognition of characteristic pigmentation and histological features is essential for diagnosis.
CONCLUSION: Ochronosis should be considered in unexplained tendon ruptures. Surgical repair and metabolic management, including nitisinone, can optimize outcomes.