Cytotoxic lesion of the corpus callosum (CLOCC) associated with typhoid fever: A case report.

Cytotoxic lesions of the corpus callosum (CLOCCs) are rare but significant abnormalities characterized by transient lesions in the splenium of the corpus callosum, often reversible after the treatment of the underlying condition. These lesions, first described in 1990, are associated with various aetiologies, including infections, metabolic disorders, and trauma. In this context, we report the case of a 44-year-old man with typhoid fever and neurological manifestations, in whom cerebral imaging revealed a cytotoxic lesion of the corpus callosum, thus highlighting this rare pathology.