Distinct Patterns of Colorectal Peritoneal Metastases at Initial and Repeat Cytoreductive Surgery.

Colorectal cancer rates are continually increasing in Western countries exceeding over 3 million new cases annually. Hematogenous spread to the liver is the most common metastatic route, followed by transcoelomic dissemination to the peritoneum. Colorectal peritoneal metastases (CRPM) affect 5%-8% at the time of initial diagnosis and a further 10%-20% who develop recurrence. Cytoreductive surgery (CRS) is the gold-standard treatment for selected patients to achieve locoregional control.