[Neurofibroma with mucus-producing glands. Report of a case and literature review].

INTRODUCTION

Most tumors of peripheral nerve sheaths containing glands are malignant tumors associated with Von Recklinghausen's disease.

CLINICAL CASE: A 39 year old man consulted with a tumour on a finger of the right hand, which was not painful, and was slow growing. There was no past history of neurofibromatosis. Histological study showed a tumour of the peripheral nerve sheath, a benign type of neurofibroma containing glands. Immunohistochemical techniques confirmed that it had the stroma of a Schwannoma with well-defined glandular epithelial elements.

CONCLUSIONS

A neurofibroma with glands is considered to be a rare type of divergent differentiation, and of considerable interest to pathologists, since it must be differentiated from other tumoral lesions. Immunohistochemical study is very useful for this.