Cureus · 2026
Clinical Characteristics and Outcomes of Hospitalized Patients With COVID-19 and Type 2 Diabetes in Vietnam: A Retrospective Study.
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Huynh Thuy Anh T, Le Buu Chau, Nguyen Bao An H, Tran Trinh T, Nguyen Khanh, Van Phuong Trang, Nguyen Thu Thao, Nguyen Tien Thanh, Ton Vinh Khoa T, Le Diem T
Аннотация
OBJECTIVE: To describe the clinical characteristics and outcomes of hospitalized patients with COVID-19 and diabetes mellitus in Vietnam.
MATERIALS AND METHODS: A retrospective descriptive study was carried out from June 2021 to September 2022 at the Hospital for Tropical Diseases, a tertiary care center in Ho Chi Minh City, Vietnam.
RESULTS: The study included 154 patients with COVID-19 and diabetes mellitus. The mean age was 65 years, and women accounted for 64.3% of the study population. Prior COVID-19 vaccination was documented in 39.6% of patients. The mean duration of illness before hospitalization was 5 ± 3 days (range, one to 15 days). At admission, 71.8% of patients required oxygen support. The most common clinical manifestations were cough, dyspnea, and fever, while chest pain and diarrhea were less frequently observed. Common in-hospital complications included cytokine storm, acute respiratory distress syndrome (ARDS), sepsis, septic shock, ventilator-associated pneumonia, and urinary tract infection. Less frequent complications were ketoacidosis, hyperosmolar hyperglycemic state, and myocardial infarction. Most patients had a previous diagnosis of diabetes, whereas 14.3% were newly diagnosed during hospitalization on the basis of glycated hemoglobin (HbA1c). The mean length of hospital stay was 16 ± 10 days (range, two to 71 days), and the mortality rate was 20%.
CONCLUSION: Hospitalized patients with COVID-19 and diabetes mellitus had a substantial clinical burden, reflected by frequent oxygen requirements, severe complications, prolonged hospitalization, and considerable mortality. These findings underscore the need for close monitoring and careful metabolic management in this high-risk population.
MATERIALS AND METHODS: A retrospective descriptive study was carried out from June 2021 to September 2022 at the Hospital for Tropical Diseases, a tertiary care center in Ho Chi Minh City, Vietnam.
RESULTS: The study included 154 patients with COVID-19 and diabetes mellitus. The mean age was 65 years, and women accounted for 64.3% of the study population. Prior COVID-19 vaccination was documented in 39.6% of patients. The mean duration of illness before hospitalization was 5 ± 3 days (range, one to 15 days). At admission, 71.8% of patients required oxygen support. The most common clinical manifestations were cough, dyspnea, and fever, while chest pain and diarrhea were less frequently observed. Common in-hospital complications included cytokine storm, acute respiratory distress syndrome (ARDS), sepsis, septic shock, ventilator-associated pneumonia, and urinary tract infection. Less frequent complications were ketoacidosis, hyperosmolar hyperglycemic state, and myocardial infarction. Most patients had a previous diagnosis of diabetes, whereas 14.3% were newly diagnosed during hospitalization on the basis of glycated hemoglobin (HbA1c). The mean length of hospital stay was 16 ± 10 days (range, two to 71 days), and the mortality rate was 20%.
CONCLUSION: Hospitalized patients with COVID-19 and diabetes mellitus had a substantial clinical burden, reflected by frequent oxygen requirements, severe complications, prolonged hospitalization, and considerable mortality. These findings underscore the need for close monitoring and careful metabolic management in this high-risk population.