The journal of trauma and acute care surgery · 2014
Evaluation of the oxygenation index in adult respiratory failure.
Сравнительное исследованиеОценочное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Dechert Ronald E, Park Pauline K, Bartlett Robert H
Аннотация
BACKGROUND: The oxygenation index (mean airway pressure × FIO2 divided by PaO2) was originally devised to measure severity of illness and predict outcome in neonatal respiratory failure. We evaluated the discrimination of a modified oxygenation index (modified with age) for predicting 28-day mortality in adults with respiratory failure (adult respiratory distress syndrome [ARDS]) using the ALVEOLI section of the ARDSNet database and validated the results in the full ARDSNet database.
METHODS: We compared age-adjusted oxygenation index (AOI) on ventilator Days 1 to 4 with 28-day mortality.
RESULTS: AOI correlated positively with mortality (area under the receiver operating characteristic curve, 0.70-0.74, for ARDS Days 1-4). Following initial development, AOI related to mortality was validated in two other ARDSNet databases producing similar results (area under the receiver operating characteristic curve, 0.70-0.78).
CONCLUSION: The observed sensitivity and specificity analysis demonstrated that AOI is equivalent to or better than other mortality prediction systems used for ARDS.
LEVEL OF EVIDENCE: Prognostic, level III.
METHODS: We compared age-adjusted oxygenation index (AOI) on ventilator Days 1 to 4 with 28-day mortality.
RESULTS: AOI correlated positively with mortality (area under the receiver operating characteristic curve, 0.70-0.74, for ARDS Days 1-4). Following initial development, AOI related to mortality was validated in two other ARDSNet databases producing similar results (area under the receiver operating characteristic curve, 0.70-0.78).
CONCLUSION: The observed sensitivity and specificity analysis demonstrated that AOI is equivalent to or better than other mortality prediction systems used for ARDS.
LEVEL OF EVIDENCE: Prognostic, level III.
Предметные рубрики MeSH
AdultBlood Gas AnalysisCohort StudiesCritical CareDatabases, FactualFemaleFollow-Up StudiesHospital MortalityHumansIntensive Care UnitsLogistic ModelsMaleMiddle AgedOximetryOxygenOxygen ConsumptionPredictive Value of TestsROC CurveRespiration, ArtificialRespiratory Distress SyndromeRetrospective StudiesRisk AssessmentSeverity of Illness IndexSurvival RateTime FactorsTreatment Outcome