Ophthalmic surgery, lasers & imaging retina · 2025
Difluprednate for the Treatment of Postoperative Hypotony Following Complicated Retinal Detachment Surgery.
СтатьяНазвание и аннотация: Перевод в очереди
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Govindaraju Viren, Omari Amro, Saleem Zara, Jeong Daeun, Koustas Konstantinos, Shields Ryan A, Williams George A, Hassan Tarek S
Аннотация
BACKGROUND AND OBJECTIVE: This study assessed the impact of topical difluprednate on increasing intraocular pressure (IOP) in patients with hypotony following successful surgical repair of complex RD.
PATIENTS AND METHODS: A retrospective, consecutive case series was conducted on patients treated with topical difluprednate for hypotony after successful complex RD repair.
RESULTS: Medical records of 230 patients were reviewed, and 39 eyes of 39 patients were found to develop hypotony (IOP < 8 mmHg) at least 1 month after their last surgery. Patients presented with hypotony at a mean of 41 days after their last surgery. After initiation of topical difluprednate, there was a statistically significant increase in mean IOP from the initial (5.6 mmHg) to final visit (8.6 mmHg, P = 0.032). At the last follow-up visit, one patient had progressed to phthisis bulbi.
CONCLUSION: Topical difluprednate therapy for hypotony following successful complex RD repair resulted in a statistically significant increase in IOP. [Ophthalmic Surg Lasers Imaging Retina 2025;56:266-272.].
PATIENTS AND METHODS: A retrospective, consecutive case series was conducted on patients treated with topical difluprednate for hypotony after successful complex RD repair.
RESULTS: Medical records of 230 patients were reviewed, and 39 eyes of 39 patients were found to develop hypotony (IOP < 8 mmHg) at least 1 month after their last surgery. Patients presented with hypotony at a mean of 41 days after their last surgery. After initiation of topical difluprednate, there was a statistically significant increase in mean IOP from the initial (5.6 mmHg) to final visit (8.6 mmHg, P = 0.032). At the last follow-up visit, one patient had progressed to phthisis bulbi.
CONCLUSION: Topical difluprednate therapy for hypotony following successful complex RD repair resulted in a statistically significant increase in IOP. [Ophthalmic Surg Lasers Imaging Retina 2025;56:266-272.].