Carbamazepine-induced acute pancreatitis: rare manifestation of drug reaction with eosinophilia and systemic symptoms syndrome.

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe, delayed T-cell-mediated adverse drug reaction that affects visceral organs. Typical features include fever, rash, lymphadenopathy, haematological abnormalities and various visceral organ involvements, usually appearing 2-8 weeks after drug initiation. Although commonly affected organs include the liver, kidneys and lungs, pancreatic involvement is rare. We report a rare case of acute pancreatitis associated with DRESS syndrome due to carbamazepine. To the best of our knowledge, this is the first report identifying carbamazepine as a cause of DRESS-related acute pancreatitis.