New Hidradenitis Suppurativa in Children: Influence of Neighborhood Socioeconomic Status.

Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition with early onset and disproportionate impact on females and African American youth. In our cross-sectional study of 9695 pediatric HS patients in a single US health system, pediatric patients residing in neighborhoods with lower SES had greater odds of having a new HS diagnosis in unadjusted models and after sequential adjustment for age, sex, and race and ethnicity. Fully adjusted odds ratios (95% confidence intervals) were neighborhood SES quintile, Q1 (lowest): 4.05 (1.76-9.32), Q2: 2.86 (1.13-7.22), Q3: 2.94 (1.22-7.09), Q4: 1.46 (0.55-3.90) (p for linear trend < 0.001), with similar findings in sensitivity analyses. These findings suggest neighborhood factors may contribute to HS diagnosis, highlighting the need to identify and address modifiable, neighborhood factors that influence HS diagnosis.