The Journal of clinical endocrinology and metabolism · 2012
Clinical review: Disorders of water homeostasis in neurosurgical patients.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Hannon Mark J, Finucane Francis M, Sherlock Mark, Agha Amar, Thompson Christopher J
Аннотация
CONTEXT: Disorders of water balance are common in neurosurgical patients and usually manifest as hypo- or hypernatremia. They are most commonly seen after subarachnoid hemorrhage, traumatic brain injury, with intracranial tumors, and after pituitary surgery.
SETTING: We reviewed the experience of endocrine evaluation and management of disorders of salt and water balance in a large cohort of inpatients attending the national neurosciences referral centre in Dublin, Ireland, and compared this experience with findings from other studies.
PATIENTS: The study group included unselected neurosurgical patients admitted to our centre and requiring endocrine evaluation.
INTERVENTIONS: We conducted investigations to determine the underlying mechanistic basis for disorders of salt and water balance in neurosurgical patients and treatment to restore normal metabolism.
MAIN OUTCOME MEASURES: Morbidity and mortality associated with deranged salt and water balance were measured.
RESULTS: The underlying pathophysiology of disordered water balance in neurosurgical patients is complex and varied and dictates the optimal therapeutic approach.
CONCLUSIONS: A systematic and well-informed approach is needed to properly diagnose and manage disorders of salt and water balance in neurosurgical patients.
SETTING: We reviewed the experience of endocrine evaluation and management of disorders of salt and water balance in a large cohort of inpatients attending the national neurosciences referral centre in Dublin, Ireland, and compared this experience with findings from other studies.
PATIENTS: The study group included unselected neurosurgical patients admitted to our centre and requiring endocrine evaluation.
INTERVENTIONS: We conducted investigations to determine the underlying mechanistic basis for disorders of salt and water balance in neurosurgical patients and treatment to restore normal metabolism.
MAIN OUTCOME MEASURES: Morbidity and mortality associated with deranged salt and water balance were measured.
RESULTS: The underlying pathophysiology of disordered water balance in neurosurgical patients is complex and varied and dictates the optimal therapeutic approach.
CONCLUSIONS: A systematic and well-informed approach is needed to properly diagnose and manage disorders of salt and water balance in neurosurgical patients.