Surgical neurology international · 2024
Clipping first policy for middle cerebral artery aneurysm: A single-center cohort study.
СтатьяНазвание и аннотация: Перевод в очереди
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Dokponou Yao Christian Hugues, Oudrhiri Mohammed Yassaad, Boutarbouch Mahjouba, Arkha Yasser, Melhaoui Adyl, Hakkou Mehdi, El Khamlichi Abdeslam, El Ouahabi Abdessamad
Аннотация
BACKGROUND: The management choice for the middle cerebral artery aneurysms (MCAAs) is still controversial. This review aims to describe a single-center "clipping first" policy for MCAA over 40 years of experience and compare the short- and long-term clinical outcomes by aneurysm's location.
METHODS: This retrospective cohort study reviews the whole series of a single-center intracranial aneurysm mainly based on the micro-neurosurgical experience of the senior authors (EOA and EKA). More than 968 aneurysm patients were treated at the University Hospital "Hôpital des Spécialités" Ibn Sina of Rabat in Morocco since 1983. We have included aneurysmal subarachnoid hemorrhage patients with the World Federation of Neurosurgical Societies (WFNS) Grade ≤III (64.7% clipped; 6.9% coiled) and those with WFNS Grade ≥IV (27.5% clipped; 0.9% coiled).
RESULTS: From the database of 1069 IAs in 968 patients, we depicted 218 (22.5%) patients carrying 279 (26.1%) MCAA. About 92.1% (n = 257) of the MCAAs were microsurgically clipped, and 96.3% (n = 210) were discharged with good outcomes (modified Rankin Scale [mRS] ≤2). In the post hoc test, the mean of intracerebral hemorrhage (ICH) (4.178) among the group of poor outcome patients (mRS >2) was significantly (P = 0.001) high compared to that of 0.827 good outcome patients (mRS ≤2). The negative correlation found between the dome/neck ratio and the mRS (Pearson's r = -0.023, 95%confidence interval [CI] 0.110--0.156) at admission (Pearson's r = -0.073, 95%CI 0.061--0.204) and at discharge confirmed that the wider the MCAA neck is, the more susceptible it is to have a poor prognosis.
CONCLUSION: The good clinical outcome from the microsurgically clipped patients is overwhelming and allows us to conclude that microsurgical treatment should be mostly considered for MCAA management. The patient's poor outcome with MCAA at discharge was significantly associated with ICH at admission in the frequency of 68.9%.
METHODS: This retrospective cohort study reviews the whole series of a single-center intracranial aneurysm mainly based on the micro-neurosurgical experience of the senior authors (EOA and EKA). More than 968 aneurysm patients were treated at the University Hospital "Hôpital des Spécialités" Ibn Sina of Rabat in Morocco since 1983. We have included aneurysmal subarachnoid hemorrhage patients with the World Federation of Neurosurgical Societies (WFNS) Grade ≤III (64.7% clipped; 6.9% coiled) and those with WFNS Grade ≥IV (27.5% clipped; 0.9% coiled).
RESULTS: From the database of 1069 IAs in 968 patients, we depicted 218 (22.5%) patients carrying 279 (26.1%) MCAA. About 92.1% (n = 257) of the MCAAs were microsurgically clipped, and 96.3% (n = 210) were discharged with good outcomes (modified Rankin Scale [mRS] ≤2). In the post hoc test, the mean of intracerebral hemorrhage (ICH) (4.178) among the group of poor outcome patients (mRS >2) was significantly (P = 0.001) high compared to that of 0.827 good outcome patients (mRS ≤2). The negative correlation found between the dome/neck ratio and the mRS (Pearson's r = -0.023, 95%confidence interval [CI] 0.110--0.156) at admission (Pearson's r = -0.073, 95%CI 0.061--0.204) and at discharge confirmed that the wider the MCAA neck is, the more susceptible it is to have a poor prognosis.
CONCLUSION: The good clinical outcome from the microsurgically clipped patients is overwhelming and allows us to conclude that microsurgical treatment should be mostly considered for MCAA management. The patient's poor outcome with MCAA at discharge was significantly associated with ICH at admission in the frequency of 68.9%.