Influenza and other respiratory viruses · 2026
Early COVID-19 and Severity of Subsequent Omicron Infection in Ontario Canada.
СтатьяНазвание и аннотация: Перевод в очереди
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Kassee Caroline, Shigayeva Altynay, Kandel Christopher, Farooqi Lubna, Zhong Zoe, Gingras Anne-Claude, Coleman Brenda L, Gilbert Lois, Gold Wayne L, Major Maria, Mazzulli Tony, Mubareka Samira, Valluri Srinivas Rao, Martin Catherine, Kyaw Moe H, McLaughlin John M, McGeer Allison
Аннотация
We evaluated whether having early COVID-19 reduced the severity of subsequent Omicron infection, assessing activities of daily living (ADL), healthcare utilization and illness duration. Comparisons were made between persons with (1) early COVID-19-compatible illness with a negative test, (2) early lab-confirmed SARS-CoV-2 14-26 months and (3) early lab-confirmed SAR-CoV-2 > 26 months before Omicron infection. Among 261 patients with laboratory-confirmed Omicron, 177 (68%) had COVID-19 in 2020, a median of 793 days (IQR, 659-902) prior to Omicron infection. Compared to no early COVID-19, COVID-19 14-26 months, but not > 26 months, before was associated with reduced impact on ADL during first Omicron infection (OR 0.52, 95% CI 0.29-0.93).