[Peripheral ulcerative keratitis associated with dupilumab: a case report].

A 68-year-old male developed foreign body sensation in both eyes, photophobia and tearing in the right eye approximately 6 weeks after initiating dupilumab for severe atopic dermatitis. The right eye presented a crescent-shaped superficial-stromal ulcer in the peripheral cornea with an undermined edge, which was separated from the limbus of the cornea by a clear zone. The left eye had a pannus at the limbus of the cornea. Corneal scraping, bacterial culture, and fungal culture excluded infections. The patient was administered 0.1% fluorometholone eye drops and recombinant bovine basic fibroblast growth factor eye drops. The patient's condition continued to improve during the follow-up period. At the revisit 82 days after the initial diagnosis, the corneal lesions of the right eye were basically healed, and the corrected visual acuity increased from 0.5 to 1.0.