Next research · 2026
Movement disorder emergencies at a tertiary-care center in West Bengal, India: Spectrum, etiologies, diagnostic implications.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Manna Dinesh Kumar, Banik Ankur, Biswas Debsadhan, Pal Sandip, Pal Asutosh, Sau Arkaprabha, Chakravarthy Mihira, Benito-León Julián
Аннотация
BACKGROUND: Acute-onset movement disorders, often termed movement disorder emergencies, present in emergency and inpatient neurology settings and may arise from diverse causes, including potentially reversible metabolic and medication-related conditions.
OBJECTIVES: We aimed to describe the clinical phenomenology and etiological spectrum of movement disorder emergencies presenting to a tertiary care center.
METHODS: We conducted a prospective, single-center, hospital-based cross-sectional observational study over 12 months (February 2023 to January 2024) at a tertiary-care hospital in Kolkata, Eastern India. Patients aged 12 years or older with a movement disorder onset within 4 weeks were enrolled. Movement disorder presentations were categorized as hyperkinetic, hypokinetic, or mixed.
RESULTS: Eighty patients were included (mean age 48.0 years, standard deviation 18.0; 57.5% male). Hyperkinetic presentations predominated (80.0%), followed by mixed (13.7%) and hypokinetic (6.2%) presentations. The most frequent phenomenologies were hemichorea and myoclonus (18.7% each), followed by acute parkinsonism (17.5%), dystonia (16.2%), and tremor (15.0%). Mean symptom duration at presentation did not differ across movement disorder categories (p = 0.36). The movement disorder category was not associated with sex (p = 0.68), age group (p = 0.39), or timing of presentation (p = 0.632). The leading etiologies were metabolic (26.2%) and drug-induced (25.0%), followed by vascular (15.0%), functional (8.7%), and infectious (6.2%) causes. Functional etiologies presented exclusively with hyperkinetic phenomenology.
CONCLUSIONS: In this tertiary-care cohort, movement disorder emergencies were predominantly hyperkinetic, and metabolic and drug-induced causes accounted for over half of the cases. These findings support an expeditious diagnostic approach that prioritizes rapid metabolic screening, careful medication review, and targeted neuroimaging when clinically indicated.
OBJECTIVES: We aimed to describe the clinical phenomenology and etiological spectrum of movement disorder emergencies presenting to a tertiary care center.
METHODS: We conducted a prospective, single-center, hospital-based cross-sectional observational study over 12 months (February 2023 to January 2024) at a tertiary-care hospital in Kolkata, Eastern India. Patients aged 12 years or older with a movement disorder onset within 4 weeks were enrolled. Movement disorder presentations were categorized as hyperkinetic, hypokinetic, or mixed.
RESULTS: Eighty patients were included (mean age 48.0 years, standard deviation 18.0; 57.5% male). Hyperkinetic presentations predominated (80.0%), followed by mixed (13.7%) and hypokinetic (6.2%) presentations. The most frequent phenomenologies were hemichorea and myoclonus (18.7% each), followed by acute parkinsonism (17.5%), dystonia (16.2%), and tremor (15.0%). Mean symptom duration at presentation did not differ across movement disorder categories (p = 0.36). The movement disorder category was not associated with sex (p = 0.68), age group (p = 0.39), or timing of presentation (p = 0.632). The leading etiologies were metabolic (26.2%) and drug-induced (25.0%), followed by vascular (15.0%), functional (8.7%), and infectious (6.2%) causes. Functional etiologies presented exclusively with hyperkinetic phenomenology.
CONCLUSIONS: In this tertiary-care cohort, movement disorder emergencies were predominantly hyperkinetic, and metabolic and drug-induced causes accounted for over half of the cases. These findings support an expeditious diagnostic approach that prioritizes rapid metabolic screening, careful medication review, and targeted neuroimaging when clinically indicated.