Journal of dental sciences · 2024
Temporal stability of tongue microbiota in older patients - A pilot study.
СтатьяНазвание и аннотация: Перевод в очереди
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Tsai Fa-Tzu, Yang Cheng-Chieh, Lin Yu-Cheng, Hsu Ming-Lun, Hong Guang, Yang Mu-Chen, Wang Ding-Han, Huang Lin-Jack, Lin Chiu-Tzu, Hsu Wun-Eng, Tu Hsi-Feng
Аннотация
BACKGROUND/PURPOSE: Healthy states of human microbiota depend on a stable community of symbiotic microbes irrespective of external challenges from the environment. Thus, long-term stability of the oral microbiota is of importance, particularly for older patient populations.
MATERIALS AND METHODS: We used next-generation sequencing (NGS) to examine the tongue microbiota of 18 individuals receiving long-term care over a 10-month period.
RESULTS: Beta diversity analysis demonstrated temporal stability of the tongue microbiota, as microbial compositions from all time points were indistinguishable from each other (P = 0.0887). However, significant individual variation in microbial composition (P = 0.0001) was observed, underscoring the presence of a unique microbial profile for each patient.
CONCLUSION: The temporal dynamics of tongue microbiota exhibit long-term stability, providing diagnostic implications for oral diseases within older patient populations.
MATERIALS AND METHODS: We used next-generation sequencing (NGS) to examine the tongue microbiota of 18 individuals receiving long-term care over a 10-month period.
RESULTS: Beta diversity analysis demonstrated temporal stability of the tongue microbiota, as microbial compositions from all time points were indistinguishable from each other (P = 0.0887). However, significant individual variation in microbial composition (P = 0.0001) was observed, underscoring the presence of a unique microbial profile for each patient.
CONCLUSION: The temporal dynamics of tongue microbiota exhibit long-term stability, providing diagnostic implications for oral diseases within older patient populations.