Assessment of vitiligo in clinical practice: a cross-sectional survey among experts.
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Duponselle Jolien, Jukema Marlide R, Wolkerstorfer Albert, Ezzedine Khaled, Hamzavi Iltefat, Seneschal Julien, Eleftheriadou Viktoria, Pandya Amit G, Garg Amit, Ganesan Anand, Goh Boon Kee, Parsad Davinder, Ghia Deepti, Rosmarin David, Leone Giovanni, Lim Henry W, Ju Hyun Jeong, Bae Jung Min, Ferguson John, Benzekri Laila, Abdallah Marwa, Böhm Markus, Picardo Mauro, Rashighi Mehdi, Ramam M, Rodrigues Michelle, Raboobee Noufal, Spuls Phyllis, Esmat Samia, Thng Steven Tien Guan, Passeron Thierry, Huang Victor, Speeckaert Reinhart, van Geel Nanja
Аннотация
OBJECTIVE: This study aimed to investigate outcomes and characteristics currently assessed by vitiligo experts in clinical practice and represents one of the steps toward developing a core outcome set (COS) including outcomes and outcome measurement instruments for clinical practice.
METHODS: A cross-sectional survey was conducted among 31 vitiligo experts from six continents. The survey consisted of 28 predefined outcomes and characteristics. Participants were given the opportunity to propose additional options, which were considered 'generally assessed' when assessed by ≥ 70%.
RESULTS: Six outcomes and 21 characteristics were 'generally assessed'. The most frequently chosen outcomes included vitiligo evolution, tolerability of treatment/adverse events, followed by disease activity and vitiligo extent.
CONCLUSION: This study shows similarities but also remarkable differences in assessed outcomes compared to the CDS for clinical trials. These results serve as a preparatory step toward developing a COS for clinical practice with the involvement of expert and non-expert dermatologists and patients.