Medical journal of the Islamic Republic of Iran · 2025
Evaluation of Inspiratory Muscle Training Effect Compared With Diaphragmatic Breathing in Respiratory Parameters in Amyotrophic Lateral Sclerosis Patients: A Randomized Controlled Trial.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Mirenayat Maryam Sadat, Fakharian Atefeh, Valizadeh Melika, Abedi Mohsen, Sadeghi Somayeh, Zahiri Reyhaneh, Haghi Ashtiani Bahram, Masaebi Fatemeh, Zamani Babak
Аннотация
BACKGROUND: Many patients with amyotrophic lateral sclerosis (ALS) experience respiratory failure. The use of respiratory muscle training exercises can improve the respiratory function of these patients. This study aimed to evaluate the effect of inspiratory muscle training (IMT) on respiratory muscle function in ALS patients.
METHODS: In the current randomized controlled clinical trial study, 22 patients were randomly divided into intervention (n = 11) and control groups (n = 11). In the control group, patients used only chest-opening training and diaphragm exercises. Patients in the intervention group used IMT in addition to controlled exercises (chest opening training and diaphragm exercises). Respiratory function by spirometry and monitoring of maximum inspiratory and expiratory pressure, functional capacity with a 6-minute walk test, and arterial blood gases were also assessed by ABG analysis at baseline and after 8 weeks. A comparative analysis of variables was performed with a student t-test, considering type 1 error (α = 0.05) using SPSS 27 software.
RESULTS: The indexes included maximal inspiratory pressure (PImax) (P = 0.000) and maximal expiratory pressures PEmax (P = 0.002). The strength of breathing muscles index (S-index) (P = 0.002) had a significant increase before and after rehabilitation in both groups (P ˂ 0.05). In intergroup analysis, the only factor with a significant increase was PImax (P = 0.019).
CONCLUSION: The use of IMT, along with chest opening training and diaphragm exercises, can cause a relative improvement of the respiratory muscles' function indexes, especially PImax in ALS patients. More clinical trials are required.
METHODS: In the current randomized controlled clinical trial study, 22 patients were randomly divided into intervention (n = 11) and control groups (n = 11). In the control group, patients used only chest-opening training and diaphragm exercises. Patients in the intervention group used IMT in addition to controlled exercises (chest opening training and diaphragm exercises). Respiratory function by spirometry and monitoring of maximum inspiratory and expiratory pressure, functional capacity with a 6-minute walk test, and arterial blood gases were also assessed by ABG analysis at baseline and after 8 weeks. A comparative analysis of variables was performed with a student t-test, considering type 1 error (α = 0.05) using SPSS 27 software.
RESULTS: The indexes included maximal inspiratory pressure (PImax) (P = 0.000) and maximal expiratory pressures PEmax (P = 0.002). The strength of breathing muscles index (S-index) (P = 0.002) had a significant increase before and after rehabilitation in both groups (P ˂ 0.05). In intergroup analysis, the only factor with a significant increase was PImax (P = 0.019).
CONCLUSION: The use of IMT, along with chest opening training and diaphragm exercises, can cause a relative improvement of the respiratory muscles' function indexes, especially PImax in ALS patients. More clinical trials are required.