Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2012
Apathetic thyrotoxicosis secondary to atypical subacute thyroiditis.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Carluccio Alessia L, Sundaram Nina K, Yanagisawa Robert T, Tomer Yaron
Аннотация
OBJECTIVE: To report a case of apathetic thyrotoxicosis with an etiology of subacute thyroiditis.
METHODS: We describe the patient's clinical findings, laboratory findings, and clinical course.
RESULTS: An 85-year-old woman with no history of thyroid disease presented with severe obtundation and altered mental status. Laboratory testing documented elevated free thyroxine and free triiodothyronine concentrations and a suppressed thyrotropin concentration. Thyroid antibodies were absent. A radioactive iodine study revealed severely diminished uptake, suggestive of thyroiditis. After a short course of steroids, the patient's mental status returned to baseline. Follow-up laboratory testing showed normalizing thyroid function.
CONCLUSION: Even in the absence of a history of thyroid disease, we recommend considering thyroid dysfunction in the differential diagnosis of patients who present with altered mental status, particularly in the elderly population.
METHODS: We describe the patient's clinical findings, laboratory findings, and clinical course.
RESULTS: An 85-year-old woman with no history of thyroid disease presented with severe obtundation and altered mental status. Laboratory testing documented elevated free thyroxine and free triiodothyronine concentrations and a suppressed thyrotropin concentration. Thyroid antibodies were absent. A radioactive iodine study revealed severely diminished uptake, suggestive of thyroiditis. After a short course of steroids, the patient's mental status returned to baseline. Follow-up laboratory testing showed normalizing thyroid function.
CONCLUSION: Even in the absence of a history of thyroid disease, we recommend considering thyroid dysfunction in the differential diagnosis of patients who present with altered mental status, particularly in the elderly population.