Journal of clinical medicine · 2024
Could Vaccination against COVID-19 Trigger Immune-Mediated Inflammatory Diseases?
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Liakou Aikaterini I, Tsantes Andreas G, Routsi Eleni, Agiasofitou Efthymia, Kalamata Magdalini, Bompou Evangelia-Konstantina, Tsante Konstantina A, Vladeni Soultana, Chatzidimitriou Eleni, Kotsafti Ourania, Samonis George, Bonovas Stefanos, Stratigos Alexander I
Аннотация
Exacerbations and new onset of immune-mediated inflammatory diseases, such as psoriasis and hidradenitis suppurativa, have been reported following COVID-19 vaccination. In patients with hidradenitis suppurativa, recent studies have shown that those who received mRNA vaccines were 3.5 times as likely to develop flares following vaccination compared to patients who received non-mRNA vaccines, indicating that mRNA COVID-19 vaccines are associated with hidradenitis suppurativa flares. Similar findings have been found in other studies evaluating the association between COVID-19 vaccines and other immune-mediated inflammatory diseases such as psoriasis, atopic dermatitis, lichen planus, and alopecia areata. However, further research is warranted in larger populations to validate these findings.