The Journal of dermatological treatment · 2025
Social determinants of health, quality of life, and productivity outcomes among adults with vitiligo in Brazil, China, India, and South Africa.
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Kurosky Samantha K, Atkinson Christian, Jagun Oladayo, Cooper Charley, Lejeune Alexandre, Castellano Giorgio, Reynolds Neil, Llamado Lyndon, Makgoeng Solomon, de Castro Caio Cesar Silva, Parsad Davinder, Raboobee Noufal, Gao Xing-Hua, Lemeshow Adina R
Аннотация
OBJECTIVES: Vitiligo is an autoimmune disease resulting in skin depigmentation and individuals report substantial psychosocial burden. However, vitiligo-related quality of life impacts appear heterogeneous and may be influenced by social determinants of health. This cross-sectional survey aimed to describe characteristics and vitiligo-related quality of life impacts among adults in Brazil, China, India, and South Africa.
METHODS: Results were stratified by country and examined by bivariate analysis.
RESULTS: Respondents (n = 2202) were mean (standard deviation) 36.9 (11.5) years of age. The most frequently reported income quartile was the highest quartile in China, India, and South Africa, and second-lowest quartile in Brazil. Mean time since initial diagnosis was 11.7 years. Mean % body surface area with depigmentation ranged from 3.7% (China) to 9.7% (South Africa). Mean Dermatology Life Quality Index scores ranged from 5.8 in Brazil to 10.3 in India, indicating a 'moderate' effect of vitiligo on quality-of-life; for 32.3% of respondents, vitiligo had a 'very-to-extremely large' impact on quality-of-life. Mean daily activity impairment was 28.9%. Employed participants reported mean work impairment of 35.6%. Adults with vitiligo in Brazil, China, India, and South Africa reported diverse demographic, socioeconomic, and clinical characteristics.
CONCLUSIONS: Overall, vitiligo had a moderate impact on quality of life and was associated with reduced work productivity and activity impairments.
METHODS: Results were stratified by country and examined by bivariate analysis.
RESULTS: Respondents (n = 2202) were mean (standard deviation) 36.9 (11.5) years of age. The most frequently reported income quartile was the highest quartile in China, India, and South Africa, and second-lowest quartile in Brazil. Mean time since initial diagnosis was 11.7 years. Mean % body surface area with depigmentation ranged from 3.7% (China) to 9.7% (South Africa). Mean Dermatology Life Quality Index scores ranged from 5.8 in Brazil to 10.3 in India, indicating a 'moderate' effect of vitiligo on quality-of-life; for 32.3% of respondents, vitiligo had a 'very-to-extremely large' impact on quality-of-life. Mean daily activity impairment was 28.9%. Employed participants reported mean work impairment of 35.6%. Adults with vitiligo in Brazil, China, India, and South Africa reported diverse demographic, socioeconomic, and clinical characteristics.
CONCLUSIONS: Overall, vitiligo had a moderate impact on quality of life and was associated with reduced work productivity and activity impairments.