International journal of pharmaceutics · 2025
New advances in pressure ulcer treatment - the promoting effect of biomaterials on drugs.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Song Liwan, Luo Jialei, Xu Yana, Zhang Yunting, Gao Jianqing, Yang Gaoyi, Luo Ying
Аннотация
Wound healing is a complex process. Due to the influence of multiple factors on its progression, its management and treatment remain highly challenging. Pressure ulcers are a type of chronic wounds caused by prolonged pressure on the skin. In recent years, significant efforts have been devoted to developing novel therapies for the prevention and treatment of pressure ulcers. However, conventional drugs and clinical therapies are often limited in efficacy, fail to achieve optimal therapeutic outcomes. Consequently, novel biomaterials have been developed, with particular attention given to their ability to enhance the performance of drugs. This article outlines the healing process of pressure ulcers and summarizes the current clinical strategies for their prevention and treatment. It further reviews novel biomaterials for pressure ulcer management, focusing on their intrinsic therapeutic properties and their role in enhancing drug delivery. This review aims to contribute to future advances in the prevention and treatment of pressure ulcers.