Pediatric radiology · 1996
Hypervitaminosis A as a complication of treatment for neuroblastoma.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Grissom L E, Griffin G C, Mandell G A
Аннотация
A case of hypervitaminosis A (HVA) as a complication of therapy for stage-IV neuroblastoma is presented. The patient was randomized to a trial of 13-cis -retinoic acid (a vitamin A-related compound) after completing routine chemotherapy. This acid was given as a means of maturing potential minimal residual disease. A routine follow-up bone scan revealed areas of increased activity, initially along the midshaft of the right ulna and subsequently bilaterally, which were ultimately found to be due to HVA. Hypervitaminosis A has not been previously reported in this setting, and awareness of the condition is important in centers where this treatment is contemplated.