Intestinal Lipoma as a Cause of Sigmoid Colo-Colic Intussusception in an Adult: A Case Report.

Adult intussusception is an uncommon and often unexpected diagnosis, typically driven by an underlying structural lesion. We report the case of a 43-year-old woman who presented with a month-long constipation, five days of worsening intermittent abdominal pain associated with nausea, bilious vomiting, and anorexia. Contrast-enhanced computed tomography (CECT) revealed a sigmoid colo-colic intussusception caused by a 4 cm intraluminal fat-density mass consistent with a lipoma. The patient underwent successful surgical reduction with segmental resection and primary anastomosis. Histopathology confirmed a submucosal lipoma of the sigmoid colon. This rare presentation highlighted the pivotal role of CT imaging in identifying adult intussusception and reinforces surgical resection as the optimal management strategy when a pathological lead point is present.