Journal of affective disorders · 2026
Sleep and bipolar disorder: Associations with delivery and neonatal outcomes.
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Hendriks Sanne M, Stevens Anja W M M, Geerling Bart
Аннотация
INTRODUCTION: This study aims to examine the relationship between sleep duration and sleep quality during pregnancy and the delivery and neonatal outcomes in a prospective cohort of pregnant women with bipolar disorder (BD).
METHODS: Data were from the Sleepreg-Bipolar Disorder (Sleepreg-BD) study and included 65 pregnant Dutch women. Quality and duration of sleep were measured using actigraphy and a sleepdiary, respectively. The Altman Self-Rating Mania Scale (ASRM) and the Quick Inventory of Depressive Symptomatology (QIDS) were used to measure the severity of manic and depressive symptoms, respectively.
RESULTS: The mean sleep efficiency in trimester 2 was 76,95% (SD 8,52), and in trimester 3 74,8% (SD 7,86). The mean sleep duration in trimester 2 was 408,95 min (SD 64,10), and in trimester 3412,18 min (SD 77,69). Shorter sleep duration during trimester 2 indicated a higher risk for caesarean section. However, this association remained not significant when confounders were entered into the Model. No other associations for delivery and neonatal outcomes were found.
CONCLUSION: Although associations with delivery and neonatal outcomes were largely not observed in this cohort, sleep disturbances during pregnancy remain clinically important for maternal well-being and postpartum psychiatric risk for women with BD.
METHODS: Data were from the Sleepreg-Bipolar Disorder (Sleepreg-BD) study and included 65 pregnant Dutch women. Quality and duration of sleep were measured using actigraphy and a sleepdiary, respectively. The Altman Self-Rating Mania Scale (ASRM) and the Quick Inventory of Depressive Symptomatology (QIDS) were used to measure the severity of manic and depressive symptoms, respectively.
RESULTS: The mean sleep efficiency in trimester 2 was 76,95% (SD 8,52), and in trimester 3 74,8% (SD 7,86). The mean sleep duration in trimester 2 was 408,95 min (SD 64,10), and in trimester 3412,18 min (SD 77,69). Shorter sleep duration during trimester 2 indicated a higher risk for caesarean section. However, this association remained not significant when confounders were entered into the Model. No other associations for delivery and neonatal outcomes were found.
CONCLUSION: Although associations with delivery and neonatal outcomes were largely not observed in this cohort, sleep disturbances during pregnancy remain clinically important for maternal well-being and postpartum psychiatric risk for women with BD.