Appendicular Schistosomiasis Presenting as Peritonitis in the Eastern Province of Saudi Arabia: A Case Report.

We report the case of a 17-year-old Yemeni male with no prior medical or surgical history who presented with generalized abdominal pain, nausea, vomiting, anorexia, and diarrhea. Initial clinical and radiological evaluations suggested diffuse peritonitis, with findings consistent with appendicitis. The patient underwent an open laparotomy and appendectomy, which revealed a perforated appendix with purulent contamination. Histopathological examination confirmed schistosomal ova in the appendix. Postoperative complications included a fluid collection, which was managed with targeted antibiotics. The patient was also treated with praziquantel and eventually recovered well. This case highlights the rare occurrence of schistosomiasis presenting as appendicular peritonitis and emphasizes the importance of considering parasitic infections in acute abdominal presentations, particularly in endemic regions.