Respiratory physiology & neurobiology · 2025
Effects of threshold inspiratory muscle trainer versus trigger sensitivity adjustment versus conventional therapy on respiratory function in mechanically ventilated patients: a randomized controlled trial.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Abdeen Heba A A, Atef Hady, Elnahas Nesreen G, Khalaf Omnia A, Soliman Youssef M A, Elkorashy Reem I M, Mowad Samah, Moreno-Segura Noemi, Carrasco Juan Jose, Marques-Sule Elena
Аннотация
BACKGROUND: Prolonged mechanical ventilation in chronic obstructive pulmonary disease is associated with severe complications, and then earlier weaning is desirable. Then, strategies such as inspiratory muscle training (IMT) have been studied. This study aimed to compare the effects of IMT via Threshold device versus trigger sensitivity adjustment of the mechanical ventilator versus conventional therapy on respiratory parameters on chronic obstructive pulmonary disease weaning patients.
METHODS: Ninety patients (aged 50-70) with acute respiratory failure on mechanical ventilation selected from the Intensive Care Unit were randomly assigned into: IMT via Threshold and conventional physical therapy group; trigger sensitivity adjustment of the mechanical ventilator and conventional physical therapy group; and conventional physical therapy alone group. Negative inspiratory force (NIF), respiratory rate (RR), tidal volume (VT), rapid shallow breathing index (RSBI), pH, and oxygenation parameters (PaO2, PaCO2, and P/F ratio) were measured pre and post-treatment.
RESULTS: Threshold group showed higher improvements in NIF than the trigger sensitivity adjustment group (p = 0.002; ES: 0.91). Threshold group showed better results in all measures than conventional physical therapy group except for pH and PaCO2. Trigger sensitivity adjustment and conventional physical therapy groups showed significant improvements in all measurements (p < 0.005 for NIF (2.30), RR (1.69), VT (0.80); RSBI (2.09), PaO2 (1.20), P/F ratio (1.22) except for VT, pH, and PaCO2 with preference to trigger sensitivity adjustment group. No significant differences were found in the percentage of weaning between groups, but Threshold group showed significantly lower weaning days than conventional physical therapy group (p = 0.004, ES:1.01).
CONCLUSION: The respiratory training with the IMT device has significantly higher improvements than the other techniques and reduces the weaning duration.
METHODS: Ninety patients (aged 50-70) with acute respiratory failure on mechanical ventilation selected from the Intensive Care Unit were randomly assigned into: IMT via Threshold and conventional physical therapy group; trigger sensitivity adjustment of the mechanical ventilator and conventional physical therapy group; and conventional physical therapy alone group. Negative inspiratory force (NIF), respiratory rate (RR), tidal volume (VT), rapid shallow breathing index (RSBI), pH, and oxygenation parameters (PaO2, PaCO2, and P/F ratio) were measured pre and post-treatment.
RESULTS: Threshold group showed higher improvements in NIF than the trigger sensitivity adjustment group (p = 0.002; ES: 0.91). Threshold group showed better results in all measures than conventional physical therapy group except for pH and PaCO2. Trigger sensitivity adjustment and conventional physical therapy groups showed significant improvements in all measurements (p < 0.005 for NIF (2.30), RR (1.69), VT (0.80); RSBI (2.09), PaO2 (1.20), P/F ratio (1.22) except for VT, pH, and PaCO2 with preference to trigger sensitivity adjustment group. No significant differences were found in the percentage of weaning between groups, but Threshold group showed significantly lower weaning days than conventional physical therapy group (p = 0.004, ES:1.01).
CONCLUSION: The respiratory training with the IMT device has significantly higher improvements than the other techniques and reduces the weaning duration.