Leading developments in basic research on aspergillosis and mucormycosis.

This editorial presents an overview of notable contributions in basic research on aspergillosis and mucormycosis published between 2022 and 2024. Basic research in aspergillosis saw major advances in the field of genomics brought about by inexpensive whole-genome sequencing of hundreds of isolates. This has deepened our understanding of Aspergillus fumigatus population structure, gene diversity, and the evolution of azole antifungal resistance. Basic research in mucormycosis saw interesting developments in our understanding of the interactions between Rhizopus microsporus and endosymbiotic bacteria that protect it against predatory soil amoeba and increase its virulence in models of infection.