Cancer reports (Hoboken, N.J.) · 2025
Precision Diagnosis and Individualized Therapy of Non-Gestational Choriocarcinoma Invading the Corpus Uteri and Cervix: A Case Report and Literature Review.
СтатьяКлинический случайОбзорПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ma Jiahui, Ma Fenghua, Chen Tingting, Lu Xin, Du Yan, Yue Xiaoni
Аннотация
BACKGROUND: Non-gestational choriocarcinoma (NGCC) is a rare type of malignant tumor. Primary lesions are typically detected in the ovary and rarely invade the corpus uteri and cervix. NGCC usually has a poor prognosis due to the difficulty in achieving early and accurate diagnoses because of its rarity.
CASE: This case described a female who was initially diagnosed with gestational choriocarcinoma and treated with EMA-CO chemotherapy. However, subsequent short tandem repeat (STR) analysis confirmed the diagnosis as NGCC, prompting surgical intervention. Given her favorable response and after thorough communication, three additional cycles of EMA-CO chemotherapy were recommended. At her last follow-up, her human chorionic gonadotropin level had normalized.
CONCLUSION: This case presents a rare instance of NGCC with simultaneous uterine and cervical involvement, confirmed by STR analysis and successfully managed with the EMA-CO regime. It highlights the necessity of precise diagnosis and personalized treatment for effective management of this disease.
CASE: This case described a female who was initially diagnosed with gestational choriocarcinoma and treated with EMA-CO chemotherapy. However, subsequent short tandem repeat (STR) analysis confirmed the diagnosis as NGCC, prompting surgical intervention. Given her favorable response and after thorough communication, three additional cycles of EMA-CO chemotherapy were recommended. At her last follow-up, her human chorionic gonadotropin level had normalized.
CONCLUSION: This case presents a rare instance of NGCC with simultaneous uterine and cervical involvement, confirmed by STR analysis and successfully managed with the EMA-CO regime. It highlights the necessity of precise diagnosis and personalized treatment for effective management of this disease.