Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 2026
A conceptual framework to assess health-related quality of life and treatment effectiveness in headache disorders from the patient perspective.
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Kaur Manraj N, Hazewinkel Merel H J, Mönnink Giulia L E, Tsangaris Elena, Pattanaik Rakasa, O'Gorman Joanna, Ashina Sait, Austen William G, Klassen Anne, Pusic Andrea, Gfrerer Lisa
Аннотация
BACKGROUND: We aimed to elicit concepts that are important to patients with headache disorders (HD) to develop an HD-specific conceptual framework covering health-related quality of life (HRQL) and experiences of care.
METHODOLOGY: A qualitative health services research approach was used to inform in-depth, semi-structured interviews with English-speaking adults with HD. Purposive, maximal variation sampling was used to ensure representation of a diverse sample that varied by age, gender, and HD diagnosis and treatments. A semi-structured interview guide was used that required participants to describe the impact of their HD and treatments on their HRQL and their experience of care.
RESULTS: Twenty participants (mean age 46±8.3; 75% women) were interviewed. The analysis led to developing a comprehensive conceptual framework that included two top-level domains (i.e., HRQL and experience of care). HRQL consisted of four subdomains: physical, psychological, social, and sexual wellbeing. Participants described their experience of care in terms of satisfaction with healthcare providers, treatment, and information.
CONCLUSION: The framework, derived from concept elicitation interviews, provides a comprehensive basis for future research to develop a patient-reported outcome measure to address important gaps in existing measures by capturing HRQL concerns specific to HD.
METHODOLOGY: A qualitative health services research approach was used to inform in-depth, semi-structured interviews with English-speaking adults with HD. Purposive, maximal variation sampling was used to ensure representation of a diverse sample that varied by age, gender, and HD diagnosis and treatments. A semi-structured interview guide was used that required participants to describe the impact of their HD and treatments on their HRQL and their experience of care.
RESULTS: Twenty participants (mean age 46±8.3; 75% women) were interviewed. The analysis led to developing a comprehensive conceptual framework that included two top-level domains (i.e., HRQL and experience of care). HRQL consisted of four subdomains: physical, psychological, social, and sexual wellbeing. Participants described their experience of care in terms of satisfaction with healthcare providers, treatment, and information.
CONCLUSION: The framework, derived from concept elicitation interviews, provides a comprehensive basis for future research to develop a patient-reported outcome measure to address important gaps in existing measures by capturing HRQL concerns specific to HD.