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DOI 10.1007/s10616-024-00632-3

Медицинская библиотека · Hepatobiliary & pancreatic diseases international : HBPD INT · 2002

Detection of circulating hepatocellular carcinoma cells in peripheral venous blood by reverse transcription-polymerase chain reaction.

Lin Jinrong, Chen Kaili, Liang Meng, Machain Tania Choreno, Crouch Daisy, Mengoli Simona, Exley George, Zaplluzha Alma, Baldwin Mathew, Jackson William, Cosker Thomas, Snelling Sarah, Carr Andrew, Blunn Gordon, Price Andrew, Mouthuy Pierre-Alexis

Клиническое исследованиеКонтролируемое клиническое исследованиеСтатьяПеревод в очереди

Аннотация

PURPOSE: Electrocardiogram (ECG) is one of the most essential tools for detecting heart problems. Till today most of the ECG records are available in paper form. It can be challenging and time-consuming to manually assess the ECG paper records. Hence, automated diagnosis and analysis are possible if we digitize such paper ECG records.

METHODS

The proposed work aims to convert ECG paper records into a 1-D signal and generate an accurate diagnosis of heart-related problems using deep learning. Camera-captured ECG images or scanned ECG paper records are used for the proposed work. Effective pre-processing techniques are used for the removal of shadow from the images. A deep learning model is used to get a threshold value that separates ECG signal from its background and after applying various image processing techniques threshold ECG image gets converted into digital ECG. These digitized 1-D ECG signals are then passed to another deep learning model for the automated diagnosis of heart diseases into different classes such as ST-segment elevation myocardial infarction (STEMI), Left Bundle Branch Block (LBBB), Right Bundle Branch Block (RBBB), and T-wave abnormality.

RESULTS

The accuracy of deep learning-based binarization is 97%. Further deep learning-based diagnosis approach of such digitized paper ECG records was having an accuracy of 94.4%.

CONCLUSIONS

The digitized ECG signals can be useful to various research organizations because the trends in heart problems can be determined and diagnosed from preserved paper ECG records. This approach can be easily implemented in areas where such expertise is not available.

SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40846-021-00632-0.

Для цитирования: Lin Jinrong, Chen Kaili, Liang Meng, Machain Tania Choreno, Crouch Daisy, Mengoli Simona, Exley George, Zaplluzha Alma, Baldwin Mathew, Jackson William, Cosker Thomas, Snelling Sarah, Carr Andrew, Blunn Gordon, Price Andrew, Mouthuy Pierre-Alexis. Detection of circulating hepatocellular carcinoma cells in peripheral venous blood by reverse transcription-polymerase chain reaction.. Hepatobiliary & pancreatic diseases international : HBPD INT. 2002. DOI: 10.1007/s10616-024-00632-3.

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