[Nodular form of idiopathic reactive lymphoid hyperplasia of the vestibular part of the larynx].

Laryngeal lymphoid hyperplasia is an extremely rare pathology, and clinical cases of this pathology described in the literature are limited. This article presents a clinical case of a patient with nodular idiopathic reactive lymphoid hyperplasia of the vestibular larynx. Patient G., 53 years old, was admitted to the department in April 2024 complaining of tracheostomy, difficulty swallowing, hoarseness. After the examination, the diagnosis was established: neoplasm of the larynx. Laryngeal stenosis. Tracheostomy. A neoplasm removal was performed via direct laryngoscopy under general anesthesia using radiofrequency device Surgitron and an ARC TrueBlue 445 nm surgical laser. The morphological picture was similar to a lymphoproliferative disorder. However, immunohistochemical reactions with antibodies to bcl-6 (clone GI191E/A8, Cell Marque Corporation) and to bcl-2 (clone 124, Cell Marque Corporation) canceled the diagnosis of lymphoma and established the diagnosis of supraglottic submucosa nodular idiopathic reactive lymphoid hyperplasia. The patient was decannulated and fully rehabilitated. Idiopathic lymphoid hyperplasia of the larynx is an extremely rare cause of airway stenosis that requires surgical intervention. The diagnosis should be differentiated with lymphoproliferative disorders and with foci of ectopic tonsil tissue. The diagnosis should be based on a thoroughly conducted histological examination with immunohistochemical reactions.