Journal of perinatology : official journal of the California Perinatal Association · 2026
Variations in diagnosis and management of hemodynamically significant patent ductus arteriosus across neonatal intensive care units in the Children's Hospitals Neonatal Consortium.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Gowda Sharada H, Levy Philip T, Hamrick Shannon, Keene Sarah, Sen Shawn, Rajgarhia Ayan, Rao Rakesh, Ball Molly K, Weems Mark F, CHNC Cardiac Focus Group
Аннотация
OBJECTIVE: Collate patent ductus arteriosus (PDA) guidelines among Children's Hospitals Neonatal Consortium (CHNC) centers and identify variations in the diagnosis and management of hemodynamically significant PDA (hsPDA).
STUDY DESIGN: A descriptive survey requesting written PDA guidelines was sent to CHNC representatives from November 2023 to February 2024. Our study methods were performed in accordance with the survey guidelines and regulations of the CHNC. No PHI identifiers or institutional data were utilized for performing this study.
RESULTS: Of 44 centers, 38 (86%) responded; 25 (67%) provided written guidelines. Clinical signs of PDA were included in 18 (72%) guidelines, and 21 (84%) specified echocardiographic criteria for hsPDA. Ibuprofen was the most common first-line therapy, followed by acetaminophen and indomethacin. Most centers outlined a stepwise management approach including fluid restriction, diuretics, pharmacotherapy, and transcatheter closure. Surgical ligation was less frequently recommended.
CONCLUSIONS: A majority of CHNC centers maintain written hsPDA guidelines incorporating clinical and echocardiographic criteria. Management emphasizes a stepwise approach from expectant to active management with pharmacotherapy and increasing adoption of transcatheter closure, highlighting evolving practice patterns in neonatal PDA care.
STUDY DESIGN: A descriptive survey requesting written PDA guidelines was sent to CHNC representatives from November 2023 to February 2024. Our study methods were performed in accordance with the survey guidelines and regulations of the CHNC. No PHI identifiers or institutional data were utilized for performing this study.
RESULTS: Of 44 centers, 38 (86%) responded; 25 (67%) provided written guidelines. Clinical signs of PDA were included in 18 (72%) guidelines, and 21 (84%) specified echocardiographic criteria for hsPDA. Ibuprofen was the most common first-line therapy, followed by acetaminophen and indomethacin. Most centers outlined a stepwise management approach including fluid restriction, diuretics, pharmacotherapy, and transcatheter closure. Surgical ligation was less frequently recommended.
CONCLUSIONS: A majority of CHNC centers maintain written hsPDA guidelines incorporating clinical and echocardiographic criteria. Management emphasizes a stepwise approach from expectant to active management with pharmacotherapy and increasing adoption of transcatheter closure, highlighting evolving practice patterns in neonatal PDA care.