Benign cutaneous plexiform hybrid tumour of perineurioma and cellular neurothekeoma: A rare diagnosis.

Benign cutaneous plexiform hybrid tumour of perineurioma and cellular neurothekeoma (BCPHTPCN) is an uncommon mesenchymal tumour first described in 2013, characterised by mixed features of perineurioma and cellular neurothekeoma. Clinically, it presents as a small papule, most frequently located in the perioral region. Histologically, it displays a plexiform pattern composed of epithelioid and spindle cells within a myxoid stroma, together with a hybrid immunohistochemical profile. In this article, we describe the case of an 82-year-old woman presenting with a perioral nodule clinically suspected to be a basal cell carcinoma, whose histological and immunohistochemical findings confirmed the diagnosis of BCPHTPCN. The tumour's features, differential diagnoses, and the need for further studies to better define its clinicopathological spectrum are discussed.