Neurodegenerative disease management · 2026
Pain and fatigue in amyotrophic lateral sclerosis: a multiple methods study.
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Silva Stephano Tomaz, de Queiroz Aquino Letícia Maria, Aires Diogo Neres, de Souza Aline Alves, de Macedo João Victor Barbosa, da Silva Teixeira Sabrina, de Melo Luciana Protásio, de Macedo Borges Lorenna Raquel Dantas, Lindquist Ana Raquel Rodrigues, de Medeiros Valentim Ricardo Alexsandro, Ribeiro Tatiana
Аннотация
INTRODUCTION: Pain and fatigue are frequent symptoms in individuals with Amyotrophic Lateral Sclerosis (ALS) and the literature is controversial regarding the effectiveness of physiotherapy practices for managing these symptoms.
OBJECTIVE: To analyze the profile of pain and fatigue symptoms in a Brazilian sample with ALS and identify physiotherapy practices.
METHODS: A multimethods study composed of prospective cross-sectional design and systematic retrospective design. Data on pain and fatigue were collected and literature searches were conducted and risk of bias (PEDRro scale) and evidence quality (SIGN system) were evaluated.
RESULTS: The sample (72 individuals) had a mean score of 4.31 (pain) and 37.2 (fatigue), indicating moderate levels of symptoms. The systematic review identified various physiotherapy practices for treating pain and fatigue.
CONCLUSION: Prospective analysis of pain and fatigue profiles in individuals with ALS in Brazil revealed moderate levels of both symptoms. The systematic retrospective analysis indicated uncertainty regarding the effect of physiotherapy.
OBJECTIVE: To analyze the profile of pain and fatigue symptoms in a Brazilian sample with ALS and identify physiotherapy practices.
METHODS: A multimethods study composed of prospective cross-sectional design and systematic retrospective design. Data on pain and fatigue were collected and literature searches were conducted and risk of bias (PEDRro scale) and evidence quality (SIGN system) were evaluated.
RESULTS: The sample (72 individuals) had a mean score of 4.31 (pain) and 37.2 (fatigue), indicating moderate levels of symptoms. The systematic review identified various physiotherapy practices for treating pain and fatigue.
CONCLUSION: Prospective analysis of pain and fatigue profiles in individuals with ALS in Brazil revealed moderate levels of both symptoms. The systematic retrospective analysis indicated uncertainty regarding the effect of physiotherapy.