Медицинская библиотека · Neurodegenerative disease management · 2026

Pain and fatigue in amyotrophic lateral sclerosis: a multiple methods study.

Silva Stephano Tomaz, de Queiroz Aquino Letícia Maria, Aires Diogo Neres, de Souza Aline Alves, de Macedo João Victor Barbosa, da Silva Teixeira Sabrina, de Melo Luciana Protásio, de Macedo Borges Lorenna Raquel Dantas, Lindquist Ana Raquel Rodrigues, de Medeiros Valentim Ricardo Alexsandro, Ribeiro Tatiana

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Аннотация

INTRODUCTION

Pain and fatigue are frequent symptoms in individuals with Amyotrophic Lateral Sclerosis (ALS) and the literature is controversial regarding the effectiveness of physiotherapy practices for managing these symptoms.

OBJECTIVE

To analyze the profile of pain and fatigue symptoms in a Brazilian sample with ALS and identify physiotherapy practices.

METHODS

A multimethods study composed of prospective cross-sectional design and systematic retrospective design. Data on pain and fatigue were collected and literature searches were conducted and risk of bias (PEDRro scale) and evidence quality (SIGN system) were evaluated.

RESULTS

The sample (72 individuals) had a mean score of 4.31 (pain) and 37.2 (fatigue), indicating moderate levels of symptoms. The systematic review identified various physiotherapy practices for treating pain and fatigue.

CONCLUSION

Prospective analysis of pain and fatigue profiles in individuals with ALS in Brazil revealed moderate levels of both symptoms. The systematic retrospective analysis indicated uncertainty regarding the effect of physiotherapy.

Для цитирования: Silva Stephano Tomaz, de Queiroz Aquino Letícia Maria, Aires Diogo Neres, de Souza Aline Alves, de Macedo João Victor Barbosa, da Silva Teixeira Sabrina, de Melo Luciana Protásio, de Macedo Borges Lorenna Raquel Dantas, Lindquist Ana Raquel Rodrigues, de Medeiros Valentim Ricardo Alexsandro, Ribeiro Tatiana. Pain and fatigue in amyotrophic lateral sclerosis: a multiple methods study.. Neurodegenerative disease management. 2026. DOI: 10.1080/17582024.2026.2617856.

Предметные рубрики MeSH

Humans Amyotrophic Lateral Sclerosis Fatigue Cross-Sectional Studies Pain Brazil Female Male Middle Aged Retrospective Studies Prospective Studies Physical Therapy Modalities Aged Adult Pain Management

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