Case reports in oncological medicine · 2026
Primary Mediastinal Seminoma: A Diagnostic and Therapeutic Challenge With an Optimistic Outcome.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
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Dos Santos Bueno Stephanie, Borin Previtale Roberta, Rocha Alves Mike, Soares Faico-Filho Klinger
Аннотация
INTRODUCTION: Primary mediastinal seminoma is a rare germ cell tumor that predominantly affects young men. Clinical presentation is variable, and diagnosis relies on imaging studies, tumor markers, and histopathological confirmation. This case report describes the diagnostic and therapeutic approach in a patient with mediastinal seminoma, in accordance with CARE guidelines.
CASE REPORT: A 33-year-old man presented with hoarseness, progressive dyspnea, dysphagia, and cough. Diagnostic investigation revealed a large mass in the anterior and middle mediastinum, which was confirmed as seminoma by biopsy and immunohistochemical analysis. Treatment with cisplatin-based chemotherapy (BEP regimen) resulted in a favorable response and significant tumor reduction.
CONCLUSION: Early diagnosis and appropriate treatment of primary mediastinal seminoma are essential for achieving a favorable prognosis.
CASE REPORT: A 33-year-old man presented with hoarseness, progressive dyspnea, dysphagia, and cough. Diagnostic investigation revealed a large mass in the anterior and middle mediastinum, which was confirmed as seminoma by biopsy and immunohistochemical analysis. Treatment with cisplatin-based chemotherapy (BEP regimen) resulted in a favorable response and significant tumor reduction.
CONCLUSION: Early diagnosis and appropriate treatment of primary mediastinal seminoma are essential for achieving a favorable prognosis.